Glyburide - Diabetes Management Drug

Glyburide is a medication used in the treatment of type 2 diabetes to help lower blood sugar levels by increasing insulin release from the pancreas.
Where to get
Prescription drug available at pharmacies.
Applicable for
Prepared by Lee Cheng, reviewed by Jane Cox

Glyburide FAQ

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What class of drug is glyburide?

Glyburide belongs to a class of drugs known as sulfonylureas. 7 These drugs act by closing ATP-sensitive potassium channels on pancreatic beta cells. 7 The ATP-sensitive potassium channels on beta cells are known as sulfonylurea receptor 1 (SUR1). 7

What is glyburide used for?

Glyburide is an oral diabetes medicine that helps control blood sugar levels. Glyburide is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Glyburide is not for treating type 1 diabetes.

What are the side effects of glyburide?

Common side effects include nausea, heartburn, rashes, low blood sugar, blurred vision and weight gain. Rare but serious side effects include hepatitis, jaundice, and low blood sodium levels ( hyponatremia ). What is the dosage for glyburide?

Is glyburide a sulfonylurea?

According to the American Diabetes Association (ADA) Standards of Medical Care in Diabetes 2023 update, sulfonylureas such as glyburide are considered one of the multiple options for adjunctive therapy, especially for patients seeking highly efficacious agents with a greater likelihood of achieving their glycemic goals.

Can glyburide be used to treat diabetes?

Glyburide is not used to treat type 1 diabetes (condition in which the body does not produce insulin and, therefore, cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).

Can glyburide cause low blood sugar?

The micronized tablets contain smaller particles of the drug. Glyburide is used to treat type 2 diabetes. Low blood sugar (hypoglycemia) warning: Glyburide can cause low blood sugar. Symptoms can include: If you don’t treat low blood sugar, you can have a seizure, pass out, and possibly develop brain damage. Low blood sugar can even be fatal.

Is glyburide safe?

The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Glyburide (Diabeta, Glynase PresTabs) is an oral medication used to treat type 2 diabetes. Learn about side effects, warnings, dosage, and more.

Glyburide References

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