SGLT2 Inhibitors for Type 2 Diabetes Treatment

SGLT2 inhibitors are a class of oral medications used for the treatment of type 2 diabetes. They work by reducing the reabsorption of glucose in the kidneys, leading to increased glucose excretion in the urine.
Category
Drug
Where to get
Available with a prescription from healthcare providers
Applicable for
Prepared by Lee Cheng, reviewed by Jane Cox

SGLT2 Inhibitors FAQ


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What are sodium-glucose transport protein 2 inhibitors?

Sodium-glucose transport protein 2 (SGLT2) inhibitors are a class of medications used to treat type 2 diabetes. They’re also known as gliflozins. SGLT2 inhibitors prevent the reabsorption of glucose from blood that’s filtered through your kidneys, therefore facilitating glucose excretion in the urine. This helps to lower your blood sugar levels.

How do SGLT2 inhibitors work?

SGLT2 inhibitors work in a different way to lower your blood sugar. They curb the action of proteins called "sodium-glucose cotransporter 2" that help your kidneys reabsorb glucose (sugar) from your blood. After you take SGLT2 inhibitors, less of your blood sugar ends up in your kidneys and more of it leaves your body in your urine.

Do SGLT2 inhibitors work if you have type 2 diabetes?

If you have type 2 diabetes and you've already tried other treatments, your doctor may suggest you take medications called SGLT2 inhibitors. They work by keeping blood sugar from getting absorbed back into your kidneys.

Are SGLT-2 inhibitors safe?

SGLT-2 inhibitors, also known as ‘flozins’, are tablets that were originally developed as a treatment for diabetes, but have now been found to also help your heart and your kidneys. SGLT-2 inhibitors have been shown to be very safe for kidney patients and actually protect the kidneys, slowing the decline of your renal function.

What are SGLT-2 inhibitors?

SGLT-2 inhibitors ('SGLT-2i', also known as ‘gliflozins’) are a class of drugs used in the treatment of diabetes, heart failure and chronic kidney disease. The drugs include dapagliflozin (Forxiga®), empagliflozin (Jardiance®), canagliflozin (Invokana®) and ertugliflozin (Steglatro®).

Are SGLT2 inhibitors good for 2 diabetes?

2 diabetes on SGLT2 inhibitors. This leaflet provides information regarding benefits, possible side effects including DKA and circumstances in which patients need to seek medical advice. What are SGLT2 inhibitors? • SGLT2 inhibitors are a class of drugs used in the treatment of diabetes.

What is SGLT 2 information?

It provides information on the different medication, possible side effects and when you should stop taking the medication. What are SGLT-2 inhibitors? SGLT-2 inhibitors ('SGLT-2i', also known as ‘gliflozins’) are a class of drugs used in the treatment of diabetes, heart failure and chronic kidney disease.

Who should take SGLT2 inhibitors?

SGLT2 inhibitors are usually prescribed to adults who have type 2 diabetes. They may not be suitable for some people. You should tell your doctor before starting any of this medication if you: You are easily hydrated or take a high dose of diuretics (water tablets)

SGLT2 Inhibitors References

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