Sulfonylureas for Type 2 Diabetes Treatment

Sulfonylureas are a class of oral medications used to treat type 2 diabetes by stimulating the pancreas to release more insulin.
Category
Drug
Where to get
Prescription medication available at pharmacies
Applicable for
Prepared by Lee Cheng, reviewed by Jane Cox

Sulfonylureas FAQ


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What are sulfonylureas used for?

Sulfonylureas are a group of medicines used to treat type 2 diabetes. With type 2 diabetes, the body doesn’t use the hormone insulin properly, leading to elevated levels of blood sugar (glucose). The first sulfonylureas were developed in the 1950s, notes StatPearls. The drugs work by increasing the release of insulin from the pancreas.

What are sulfonylureas?

Sulfonylureas are a group of medicines used in the management of Type 2 diabetes. Sulfonylureas lower blood glucose levels by stimulating insulin release from the Beta cells of the pancreas.

How do sulfonylureas work?

The first sulfonylureas were developed in the 1950s, notes StatPearls. The drugs work by increasing the release of insulin from the pancreas. Sulfonylureas are only one part of a treatment plan for type 2 diabetes, which should also include diet and exercise to help control blood sugar levels.

Who are sulphonylureas suitable for?

Sulphonylureas are suitable for people with type 2 diabetes with blood glucose levels that are higher than the recommended levels (an HbA1c above 6.5%) usually once metformin has been prescribed.

What are sulphonylureas used for?

Sulphonylureas are a class of medications that are commonly used to treat type 2 diabetes. They can be particularly helpful in people who have diabetes due to a problem with their genes (sometimes called monogenic diabetes) or diabetes due to steroid medication. How do Sulphonylureas work?

Do sulfonylureas work in people with Type 1 diabetes?

Sulfonylureas are a group of medicines used in the management of Type 2 diabetes. Sulfonylureas lower blood glucose levels by stimulating insulin release from the Beta cells of the pancreas. Their action is dependent upon the presence of functioning Beta cells, therefore, sulfonylureas do not work in people with type 1 diabetes.

What are the side effects of sulfonylureas?

According to StatPearls, side effects of sulfonylureas may include: Sulfonylureas shouldn’t be taken by people with type 1 diabetes or diabetic ketoacidosis (a dangerous condition that can occur if high blood sugar is left untreated). People with liver or kidney problems may not be able to take sulfonylureas.

Sulfonylureas References

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